Cirrhosis is the cause of a high rate of death in hospitals. Methodology: It is a retrospective study covering from January 1st, to December 31st, at Centre Hospitalier et Universitaire de Yopougon in Abidjan.
We concerned the cirrhosis patients that have been followed at the hepatology and gastroenterology department. Survival was estimated by the Kaplan-Meier curve and comparison of survival curves by the log-rank test. The multi-varied analysis of the survivals has been achieved with the Cox proportional Hazard regression. Cirrhosis is the final stage of development of liver fibrosis induced more by chronic liver disease. It is defined by the existence of an architectural modification diffuse hepatic parenchyma characterized by the existence of extensive fibrosis, dissecting and delimiting annular hepatocyte nodules so-called regeneration [1].
The complications of cirrhosis are frequent and potentially serious: portal hypertension, the cause of bleeding from ruptured gastroesophageal varices, hepatic encephalopathy, infection of ascites fluid, hepatorenal syndrome and hepatocellular carcinoma [2]. The management of portal hypertension with cirrhotic patients is a major concern for hospital practitioners.
It is the cause of a high rate of mortality [5] [6]. In fact, many factors predispose cirrhosis patient to the risk of unexpected arrival of a multi deep-rooted default likely to imperil the vital prognostic: immune dysregulation that will promote the risk of infection, pulmonary involvement by the hepatopulmonary syndrome, a decrease of coagulation factors and renal hypoperfusion caused by the hepatorenal syndrome [7]. The evaluation of the prognosis of cirrhotic patients followed in hospitalization would improve their care.
We conducted this study in cirrhotic patients in order to estimate the death incidence and to identify risk factors to which cirrhotic patients in Ivorian hospitals are exposed. From January through December , we consecutively enrolled patients with cirrhosis and portal hypertension who were admitted to Centre Hospitalier et Universitaire de Yopougon in Abidjan. No commercial support was involved in the study. All the authors vouch for the integrity and the accuracy of the analysis and for the fidelity of the study.
